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AB de Villiers is set to star for South Africa at Headingley next month having been declared fit to captain the side in their Royal London ODI Series and Champions Trophy.
De Villiers, 33, missed two games for IPL side Royal Challengers Bangalore because of a back injury, fuelling fears that he might not be fully fit in time.
The squad will play three ODIs against England starting with the first match at Headingley in Leeds on May 24th, before their first group match of the ICC Champions Trophy against Sri Lanka at the Oval on June 3.
Dale Steyn is yet to recover from breaking a bone in his right shoulder against Australia in November, while Vernon Philander misses out after picking up a groin injury playing for Sussex in the Specsavers County Championship.
There is a place for Morne Morkel, who has not been involved in ODI cricket for 10 months, while left-arm spinner Keshav Maharaj is included for the first time.
Standard Bank Proteas ODI squad for three-match ODI series against England and ICC Champions Trophy:
Hashim Amla (BuildNat Cape Cobras)
Quiton de Kock – wk (Multiply Titans)
Faf du Plessis (Multiply Titans)
AB de Villiers – captain (Multiply Titans)
JP Duminy (BuildNat Cape Cobras)
David Miller (VKB Knights)
Chris Morris (Multiply Titans)
Wayne Parnell (BuildNat Cape Cobras)
Andile Phehlukwayo (Hollywoodbets Dolphins)
Kagiso Rabada (bizhub Highveld Lions)
Imran Tahir (Hollywoodbets Dolphins)
Dwaine Pretorius (bizhub Highveld Lions)
Keshav Maharaj (Hollywoodbets Dolphins)
Farhaan Behardien (Multiply Titans)
Morne Morkel (Multiply Titans)
South Africa ODI Tour to UK itinerary
Fri 19 May 1-day Tour match v Sussex (D/N) 1st Central County Ground, Hove
Sun 21 May 1-day Tour match v Northants Northampton
Wed 24 May 1st Royal London ODI (D/N) Headingley, Leeds
Sat 27 May 2nd Royal London ODI Ageas Bowl, Southampton
Mon 29 May 3rd Royal London ODI Lord’s, London
Thu 1 – Mon 19 June ICC Champions Trophy
Sat 3 June Sri Lanka v South Africa The Oval, London
Wed 7 June Pakistan v South Africa Edgbaston, Birmingham
Sun 11 June India v South Africa The Oval, London